Innovative device detects prostate cancer and kidney disease on the spot.
Credit: Brigham Young University

Scientists from Brigham Young University have developed a remarkably simple device that has the potential to save lives.

The innovative device, created by chemist Adam Woolley and his students, can detect prostate cancer and kidney disease on the spot, all by simply dropping a urine sample into a tiny tube and seeing how far it goes.

This from Brigham Young University:

The tube is lined with DNA sequences that will latch onto disease markers and nothing else. Urine from someone with a clean bill of health would flow freely through the tube (the farther, the better). But even at ultra-low concentrations, the DNA grabs enough markers to slow the flow and signal the presence of disease.

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Growing microtubule endpoints and tracks are color coded by growth phase lifetime.
Credit: Betzig Lab, HHMI/Janelia Research Campus, Mimori-Kiyosue Lab, RIKEN Center for Developmental Biology

A new discovery out of Howard Hughes Medical Institute’s Janelia Research Campus is allowing biologists to see 3-D images of subcellular activity in real time.

They’re calling it lattice light sheet microscopy, and it’s providing yet another leap forward for light microscopy. The imaging platform was developed by Eric Betzig and colleagues in order to collect high-resolution images rapidly and minimize damage to cells.

Continue reading to check out the amazing video that shows the five different stages during the division of a HeLa cell as visualized by the lattice light sheet microscope.

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The dolphin ‘breathalyzer’ will analyze the for health problems and aid in wildlife conservation.
Credit: American Chemical Society

While breath analysis is most commonly known for its ability to detect alcohol consumption, it has the potential to extend far beyond that use. Breath analysis has the ability to diagnose a wide range of human conditions, and is now being utilized to aid the bottlenose dolphin.

Engineers from the University of California, Davis have developed a device for collecting dolphin breath for analysis. Because invasive techniques such as skin biopsies and blood sampling are difficult to perform on wild dolphins, this device will make it easier to check the health of the marine animals, study their biology, and aid in wildlife conservation.

This from UC Davis:

The researchers designed an insulated tube that traps breath exhaled from a dolphin’s blowhole and freezes it. They analyzed samples to create profiles of the mix of metabolites in breath, established baseline profiles of healthy animals and were able to identify changes in the breath of animals affected by disease or other factors. The researchers concluded that breath analysis could be used to diagnose and monitor problems in marine mammals – and, by extension, in ocean health as well.

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The 2014 Nobel Prize in Chemistry has been awarded “for the development of super-resolved fluorescence microscopy.”

The awardees are as follows: Eric Betzig, 54, of the Howard Hughes Medical Institute’s Janelia Research Campus in Ashburn, VA.; Stefan W. Hell, 51, of the Max Planck Institute for Biophysical Chemistry in Gottingen, and the German Cancer Research Center in Heidlberg, Germany; and William E. (W.E.) Moerner, 61, of Stanford University.

Because of these men, it is possible for us to obtain optical images at the nanometer scale and understand molecules.

This from The Royal Swedish Academy of Sciences:

For a long time optical microscopy was held back by a presumed limitation: that it would never obtain a better resolution than half the wavelength of light. Helped by fluorescent molecules the Nobel Laureates in Chemistry 2014 ingeniously circumvented this limitation. Their ground-breaking work has brought optical microscopy into the nanodimension.

Read the full article here.

The committee noted the importance of these achievements, by which we’re able to see how proteins in fertilized eggs divide into embryos and track proteins involved in Alzheimer’s or Parkinson’s disease.

“Due to their achievements, the optical microscope can now peer into the nanoworld,” said the committee.

Find out more information on the discoveries of the winners at Chemical & Engineering News.

Also, check out our past issue of Interface entitled, “25 Years of Scanning Electrochemical Microscopy.” The journal is completely open access, allowing everyone to partake in and share this wealth of information.

Find openings in your area via the ECS job board.

ECS’s job board keeps you up-to-date with the latest career opportunities in electrochemical and solid-state science. Check out the latest openings that have been added to the board:

Postdoctoral Research Associate, Photoelectrochemical Materials
The University of Toledo – Toledo, Ohio
The Ohio’s Wright Center for Photovoltaics Innovation and Commercialization at The University of Toledo, Ohio invites applications for a postdoctoral fellowship opportunity. The postdoctoral position is expected to conduct research in synthesis and characterization of oxide materials for the application of photoelectrochemical hydrogen production via water splitting.

Postdoctoral Position-Layered Semiconductor Materials
Temple University – Philadelphia, Pennsylvania
A postdoctoral position is available in the Chemistry Department at Temple University. The position resides within the confines of a newly funded Department of Energy – Energy Frontier Research Center. The focus of the Center is the rational design of layered semiconductor materials for use in energy applications, such as water splitting and carbon dioxide reduction.

Chemistry Formulation Engineer (Electroplating)
Xtalic Corporation – Marlborough, Massachusetts
Xtalic Corporation, a dynamic, growing Boston-area company, develops commercial electrolytic processes that create new metal alloys based on nanotechnology developed at the Massachusetts Institute of Technology (MIT).  We are seeking an energetic, results-oriented engineer to join our development team.

Membrane Technologist – Electrochemist for Fuel Cells
W.L. Gore – Elkton, Maryland
Gore is a technology-driven global company built on entrepreneurial innovation, integrity, and teamwork. Our diverse portfolio includes everything from high-performance fabrics and implantable medical devices to industrial manufacturing components and aerospace electronics. Through our product leadership, we’ve been changing lives and changing industries for more than 50 years.