Nanoporous gold features high effective surface area, tunable pore size, and high electrical conductivity and compatibility with traditional fabrication techniques.
Image: Ryan Chen/LLNL

Researchers from Lawrence Livermore National Laboratory and the University of California, Davis have recently published a paper showing that covering an implantable neural electrode with nanoporus gold could potentially eliminate the risk of scar tissue forming over the electrode’s surface.

Two former ECS member, Erkin Seker and Juergen Biener, were among the researchers involved with this development.

This from Lawrence Livermore National Laboratory:

The team demonstrated that the nanostructure of nanoporous gold achieves close physical coupling of neurons by maintaining a high neuron-to-astrocyte surface coverage ratio. Close physical coupling between neurons and the electrode plays a crucial role in recording fidelity of neural electrical activity.

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The nanotubes can be tumor-targeted and have a central ‘hollow’ core that can be loaded with a therapeutic payload.
Image: Jing Claussen (iThera Medical, Germany)

Gold nanotubes have multiple applications in fighting cancer, including internal nanoprobes for high-resolution imaging and drug delivery vehicles. With new research from the University of Leeds, we’re discovering that these gold nanotubes may also be able to give doctors the chance to treat cancer as soon as they spot it.

“Gold nanotubes – that is, gold nanoparticles with tubular structures that resemble tiny drinking straws – have the potential to enhance the efficacy of these conventional treatments by integrating diagnosis and therapy in one single system,” said Professor at the University of Leeds Institute for Biomedical and Clinical Science Sunjie Ye in a release.

The new study shows the first successful demonstration of biomedical use of gold nanotubes in a mouse model of human cancer. The researchers hope that these results will aid in the treatment of cancer and address the issue of high recurrence rates of tumors after surgical removal.

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